PROSOLV ® SMCC is unique in that it imparts both optimum. Kollidon® SR 50 100 150 100 75 3. 9003-39-8 - Povidone [USAN:USP:INN:BAN] - Similar structures search, synonyms, formulas, resource links, and other chemical information. Ensure that medical personnel are aware of the material(s) involved, and. 2323 Halpern, St-Laurent, Québec, Canada H4S 1S3 Telephone: 514-331-4634 Page 2 of 6 Notes to physician Symptoms may be delayed. : 120-130 ÛC Screw speed: 200 rpm Effect of screw speed on median particle size of NaCl in continuous mode. 1 / US Revision date 04/30/2015 Print Date 01/05/2016 Page 3 / 11 US-GHS(R11/011) / 05. 3: 100000-150000: A highly effective binder, for use as a stabilizer in oral and topical suspensions, as a thickener, and as a hydrophilizing agent or pore-forming agent in medical plastics. Search results for polyvinylpyrrolidone at Sigma-Aldrich. Kollidon® 90 F is a soluble high-molecular povidone with highest binding properties within the povidone range. 90 values but Kollidon® CL-SF at a concentration of 4% was found to show the best results (T 50 = 10. 2016 13:55. 0 per cent to 115. The independent variable factors selected were the weight by ratio of Aceclofenac to Kollidon 30 and the quantity of methanol in the formulation. Date HS Code Description Origin Country Port of Discharge Unit Quantity Value (INR) Per Unit (INR) Nov 22 2016: 39059990: KOLLIDON 30 (POLYVINYLPYRROLIDONE) (PVPK) (GERMANY). It is considered a synthetic povidone analog. Once the dispersion reaches the temperature at which that particular METHOCEL™ product becomes water soluble, the. Effect of kollidon 90F and poloxamer188 on etoricoxib to enhance it’s dissolution property by simple physical mixing and fusion techniques. If Kollidon 90 F is kept refrigerated, its K value decreases more slowly. Register now and get a free online MSDS binder. Last updated on Dec 20, 2018. We also manipulated the drug release from the kollidon SR KT 90% with a very low first-pass metabolism, its short biological half-life (4-6hr) produces many adverse effects, such as upper. Pregabalin undergoes negligible metabolism in humans. Molybdenum is active in the stimulation of enzymatic processes, whereby micro- and macronutrients such as ascorbic acid (vitamin C) and others are also synthesized. 0% Kollidon VA 64 2. k 90; kollidon; kollidon 12pf; kollidon 17; kollidon 17pf; kollidon 25; kollidon 30; kollidon 90; kollidon 90f; kollidon ce 50/50; kollidon k 25; kollidon k 30; kollidon k 90; lfc; lumiten pr 8450; luviskol k 12; luviskol k 17; luviskol k 25; luviskol k 30; luviskol k 60; luviskol k 80; luviskol k 90; luviskol kpo; mpk 90; n-vinyl-2-pyrrolidone. The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. 4% Dissolution 15 min: 84% 30 min: 97% Chemical stability Storage time RT 40 °C 10 months 100. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Kollidon VA 64 possesses a high plasticity of over 90 % that remains constant from 10 to 18 to 25 kN. Ashland offers a comprehensive range of Plasdone povidones (PVP). The tablets were developed with lactose, Kollidon® 90 F (povidone USP) and Poliox® WSR 301 NF (polietileneglicol NF) in different concentration ratios, based on the statistical ¨simplex¨ mixture aproach. Md has 6 jobs listed on their profile. W ater and acetonitrile (90:10) 2S (USP39) [NOTE— System suitability solution: Transfer 10mg of 7 min. 0,75 0,78 0,81 0,84 0,87 0,90 0,93 Relative density [-] Tensile Strength [N/mm²] GL 200 direct 0. Used to make drugs, hair sprays, shampoos, plasma substitutes, detergents, and adhesives; Also used in dyes (hair and textile), clarifying agents (wine, beer, and juices), thickeners (inks and paints), water binding agents (protein solutions), and protective colloids (polymers); [HSDB] "A polyvinyl polymer of variable molecular weight. 4% de crospovidona (Kollidon CL). Bei der Verpressung können eine oder zwei im 90°-Winkel angeordnete Rillen, sogenannte Bruchkerben in die Tablette eingepresst werden, um das Zerteilen der Tablette zu erleichtern. Table 2 shows the amount of ingredients used for the. Solid dispersions were formulated with an aim of improving aqueous solubility, oral bioavailability and the rate of dissolution of Carbamazepine using different hydrophyllic polymer like Polyethylene Glycol (PEG) 6000, Polyethylene Glycol (PEG) 4000, Polyethylene Glycol (PEG) 1500, kollidon 30, HPMC 6 cps, poloxamer 407 and povidone k 30. Insomnia is a common condition in the elderly and is associated with reduced quality of life and adverse outcomes. Parteck® SRP 80). PEG 1000 dimethacrylate (PEG1000DMA) is a long-chain hydrophilic, crosslinking monomer. Date HS Code Description Origin Country Port of Discharge Unit Quantity Value (INR) Per Unit (INR) Sep 12 2016: 39059990: KOLLIDON(R) 90 F (POVIDONE K-90 IP) Germany. PVP K-60 and K-90 polymer are available commercially as 45 and 20 percent aqueous solutions, respectively. Ďalšie zložky sú: povidón 25 (Kollidon 25), kyselina vínna, citronan sodný, kyselina citrónová, kyselina askorbová obalená etylcelulózou, acesulfam, draselná soľ; pomarančová aróma v prášku 57160, zázvorová aróma, farbivo MicroCap P-21-WSS-P-125, sacharóza. Thành phần: Hoạt chất: Glimepirid 2 mg Metformin hydrochlorid 500 mg Tá dược: Lactose monohydrat, Avicel M101, Natri starch glycolat, Crospovidon, Kollidon K30, Magnesi stearat, HPMC 615, HPMC 606, Talc, Titan dioxyd, PEG 6000. Pregabalin undergoes negligible metabolism in humans. Kollidon 30 solid dispersion using methanol by solvent evaporation method (Prajapathi ST et al. (PADCP), and Co-Povidone [Kollidon ® VA-64 Fine] (KVA64). Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Call a physician. 0 Total qty of binary mixture 90. Animal Cognition Brochure. Kollidon K-17. In case of Kollidon® VA 64 printlets showed fast dissolution characteristics (over 90% after 5 min) and rapid disintegration time – 4 s (7). IUPAC Name: ethenyl acetate; 1-ethenylpyrrolidin-2-one | CAS Registry Number: 25086-89-9 Synonyms: Copolyvidon, PVP/VA Copolymer, Polectron 845, Gantron PVP, Luviskol VA 64, Kolima 10, Kolima 35, Luviskol VA 28I, Luviskol VA 37E, Gantron S 860, Kollidon VA 64, Luviskol VA 37I, Luviskol VA 55E, Luviskol VA 55I, Luviskol VA 73E, Kolima 75, PVP-VA, Ganex E 535, Gantron S 630, Luviskol VA 281. Povidone formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents. 4 Spectral Information. 8μm como criterio de aceptación entonces entre el límite superior y el valor medio habría un intervalo de trabajo de 0. The product shows a decrease in release rate in both 20 and 40% ethanol media (Fig. With the analysis systems in CDR FoodLab ® range, in just 4 minutes, without titration, using micro quantity of sample you can carry out the Peroxide Value test of edible Oils and fats like Olive oil, Nuts oil, Walnut oil, Peanut oil, Sunflower oil, castor oil, Palm oil and the other vegetable oils, butter, margarine, Fish oil, coocking oil, animal fats and so on. Показания по. Plasdone K-29/32 polymer forms complexes with catechins, just as it does with many other compounds that cause discoloration of teeth. BASF Good flow, creamier Kollidon CL-SF. 5 g polymer Barrel temp. Today we solve unmet formulation needs and offer intelligent solutions for today and tomorrow's challenges in drug formulation. The N-methylated derivative of pregabalin, the major metabolite of pregabalin found in urine, accounted for 0. Plasdone K29/32, Plasdone K12, and Plasdone S630 were obtained from ISP. com - directory for chemicals and chemical suppliers Kollidon 25. Filaments for 3D printing were prepared by hot melt extrusion at 150°C with 10% and 20% w/w of haloperidol using Kollidon® VA64, Kollicoat® IR, Affinsiol™15 cP, and HPMCAS either individually. It is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. 9% of the dose. The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. org Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model Giovanna Sociali,*,1 Mirko Magnone,*,1 Silvia Ravera,† Patrizia Damonte,‡ Tiziana Vigliarolo,*. Date HS Code Description Origin Country Port of Discharge Unit Quantity Value (INR) Per Unit (INR) Sep 12 2016: 39059990: KOLLIDON(R) 90 F (POVIDONE K-90 IP) Germany. PVP k 90 (Povidon) Sitrik asit monohidrat Kollidon VA 64 (Kopovidon) Pearlitol SD (Mannitol) Aerosil (Silikon dioksit) Magnezyum stearat Kaplama. View Valentyn Mohylyuk’s profile on LinkedIn, the world's largest professional community. J Anal Pharm Res. Table 3, for example, is suitable for direct compression. An oil-free Alcatel Drytel 34 turbo-pump station was used for sample evacuation. 4% Cyclamate sodium 2. 0,0 10,0 20,0 30,0 40,0 50,0 60,0 70,0 80,0 90,0 100,0 02 4 6 8 10 12 14 16 18 time [h] released drug [%] 18kN 25kN Figure 2 Influence of compression force on the release profile of Kollidon® SR. Kollidon 90 F is the strongest wet-granulation binder on the market. 02 10 04 30 06 50 08 70 0 90 100 Normalized swell volume pH 7. Primarily used as a binder in granules and tablets, it can also be deployed to modify the viscosity of liquid dosage forms, and improve bioavailability of certain poorly soluble actives. Register now and get a free online MSDS binder. Инструкция по применению препарата Азицин: описание, состав, показания, противопоказания. Rosuvalan wurde Ihnen verschrieben, da: Sie einen hohen Cholesterinw. By submitting this form, you consent to American Pharmaceutical Review storing your email address and contact information, transmitting your contact information to the supplier(s) you selected, and customizing your experience based on the data you enter. 9003-39-8) manufacturer Qingdao Kaimosi Biochemical Technology Co. Cremophor ELP, Solutol HS15, Cremophor RH 40, Lutrol E300, Lutrol F108NF, Lutrol F68NF, Soluplus, Kolliphor TPGS, Kollidon 25, Kollidon 90 F, and Kollidon 12 PF were obtained from BASF. You can find detailed information on our product range by looking up your industry or using our Product Finder. [86-90] 1. Kollidon 90 F is an exception in that, under these conditions, its stability is guaranteed for one year, as its K value gradually decreases. Athos Foundation. 2% Microcrystalline cellulose AvicelPH101) 28. [0018] It is possible if desired to employ in addition to PVP other binders such as polyvinyl acetate (e. Register now and get a free online MSDS binder. DMSO also dissolves many inorganic salts, particularly transition metals nitrates, cyanides and dichromates. Editor's note: Some chemicals in this database contain more information than others due to the original reason this information was collected and how the compilation was accomplished. KOLLIDON® 25 | KOLLIDON® 30; KOLLIDON® 90 F ; KOLLIDON® VA 64; Liberación controlada. As shown in Figure 8 a,b, the peak near 3339 cm −1 is due to the N-H tensile vibration of the primary amine group in LA [ 45 ], which is located at 3280 cm −1 in the LA-VA extrudate. 25) in matrix tablets. , European and Japanese pharmacopoeia specifications for Povidone. 1 / US Revision date 04/30/2015 Print Date 01/05/2016 Page 3 / 11 US-GHS(R11/011) / 05. 8 solution (Fig. Kollidon 30 solid dispersion using methanol by solvent evaporation method (Prajapathi ST et al. , Polyvinylpyrrolidon (PVP), Kollidon 17 PF: alpha copolymers homopolymers kollidon poly polyvinyl polyvinylpyrrolidon polyvinylpyrrolidone povidone pvpp pyrrolidone solution vinyl. The Ajinomoto Group was founded on the aspiration to help people "EatWell, Live Well. Methocel E5 Prm, Methocel A15 Prm, and Methocel K3 Prm LV were obtained from Dow. BASF HOTLINE at 1-800-832-HELP. Pregabalin undergoes negligible metabolism in humans. sized, controlled release drug delivery system was aimed in this study. It can be combined with all conventional suspension stabilizers (thickeners, surfactants, etc. Search for a product. Granules containing a varying ratio of the binders povidone K90 and. 4% a-lactose monohydrate, 3. " and has continuously developed its business, contributed to healthy living in various regions around the world, and then created sconomic value. 7 Bulk density The bulk density of Kollidon® is determined according to Ph. Kollidon CL-SF helps dissolution process and especially improves dissolution rate of practically insoluble drugs due to. 2015;1(1):1‒3. Physicists are also fascinated by self-propulsion in such complex non-Newtonian fluids. Synonyms: Metallic stearate, Magnesium Salt. A wide variety of kollidon k25 options are available to you, 90. A Rosuvastatin Teva filmtabletta 14 db, 14×1 db, 15 db, 15×1 db, 20 db, 20×1 db, 28 db, 28×1 db, 30 db, 30×1 db, 56 db, 56×1 db, 60 db, 60×1 db, 90 db, 90×1 db, 98 db, 98×1 db, 100 db és 100×1 db filmtablettát tartalmazó buborékcsomagolásban, dobozban kerül forgalomba. In practica terapeutica se foloseste o solutie apoasa de 3,5 + 6% polivinil-pirolidona ce confine si alti compusi anorganici: 0,90% NaCI, 0,042% KCl, 0,025% CaCl 2 si 0,005% MgCl 2. The information in CAMEO Chemicals comes from a variety of data sources. Kollidon 30 (Fig. Kollidon 90 F is an exception in that, under these conditions, its stability is guaranteed for one year, as its K value gradually decreases. is a professional trade company operating Pharmaceutical Actives and Excipients, Chemical Reagent, Food Actives and expendable in lab. Kollidon VA 64 and Kollidon VA 64 Fine can be added to materials such as sorbitol, mannitol, starch, or direct compression aids, e. The example of a placebo tablet illustrated in Fig. For complete solubilization, the remainder of the water is then added as cold water or ice to lower the temperature of the dispersion. Kollidon must be stored tightly closed and protected from light at max. com Kollidon ® 30 and Kollidon ® 25 require binder quantities of 2% and 5% related to the tablet weight. J Anal Pharm Res. If Kollidon 90 F is kept refrigerated, its K value decreases more slowly. ) 683 023 - 683 265. Povidone formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents. Solid dispersions of ARM were prepared with Soluplus, Kollidon VA 64, HPMC and Eudragit EPO at weight ratios of 1:1, 1:2, 1:3 using spray drying technology, and characterized by Fourier transform infrared spectroscopy, differential scanning calorimetry (DSC), and X-ray powder diffraction (XRD) to identify the physicochemical interaction between. (Item Number, CAS Number or Chemical Name). In solution, it has excellent wetting properties and readily forms films, which makes it good as a. Cremophor ELP, Solutol HS15, Cremophor RH 40, Lutrol E300, Lutrol F108NF, Lutrol F68NF, Soluplus, Kolliphor TPGS, Kollidon 25, Kollidon 90 F, and Kollidon 12 PF were obtained from BASF. Kollidon VA 64 Kollidon 30 Hardness, 5070 90 110 130 150 170 190 11 12 Table ChewableTablets (100 mg, 500 mg, 1000 mg) FormulationAscorbic acid, powder (BASF) 42. Piroxicam can cause mild serum aminotransferase elevations and, in rare instances, leads to clinically apparent acute liver injury that can be severe and even fatal. The independent variable factors selected were the weight by ratio of Aceclofenac to Kollidon 30 and the quantity of methanol in the formulation. Kollidon® VA. PVP digunakan dalam konsentrasi 3-15%, sedikit higroskopis, tidak mengeras selama penyimpanan (karakter ini baik untuk tablet kunyah). : 120-130 ÛC Screw speed: 200 rpm Effect of screw speed on median particle size of NaCl in continuous mode. Pharmaceutical Granulation Processes, Mechanism, and the Use of Binders 2811001 1200 Granule size (GMD), um1002 100010031004 8001005 6001006 40010071008 2001009 01010 0 0. 57 and MDT = 13. Kollidon ® 12 PF (PVP K12, M w = 2000-3000 g/mol), Kollidon ® 17 PF (PVP K17, M w = 7000-11,000 g/mol), Kollidon ® 30 (PVP K30, M w = 44,000-54,000 g/mol), and Kollidon 90 ® F (PVP K90, M w = 1,000,000-1,500,000 g/mol) were kindly supplied by BASF (Ludwigshafen, Germany. KOLLIDON® 25 | KOLLIDON® 30; KOLLIDON® 90 F ; KOLLIDON® VA 64; Liberación controlada. The k number refers to the mean molecular weight of the povidone. BASF co-founded a global alliance of nearly 30 companies to advance solutions that reduce and eliminate plastic waste in the environment, especially in the ocean. Povidone K 12* Kollidon® 12PF BASF Povidone K 17* Kollidon® 17PF, Plasdone® C-15 BASF, ISP Povidone K 25 Kollidon® 25, Plasdone® K-25 BASF, ISP Povidone K 30 Kollidon® 30, Plasdone® K-29/32 BASF, ISP Povidone K 90 Kollidon® 90F, Plasdone® K-90 BASF, ISP Plasdone® K-90 D**, Plasdone® K-90 M** ISP. You can also browse global suppliers,vendor,prices,Price,manufacturers of Polyvinylpyrrolidone(9003-39-8). Pancreatin mixes several digestive enzymes produced by the exocrine cells of the pancreas. *Should you have any questions about the Crospovidone monograph, please contact Dr. PROSOLV ® SMCC is silicified microcristalline cellulose, a patented combination of 98% microcristalline cellulose (MCC) and 2% colloidal silicone dioxide (CSD). nl Bekijk het ruime assortiment drogisterij artikelen Vergelijk de shops voor de laagste prijs Bestel gemakkelijk & snel online. Call a physician. Keyword CPC PCC Volume Score; kollidon 90: 1. Инструкция по применению препарата Азицин: описание, состав, показания, противопоказания. Kollidon VA 64 is a vinylpyrrolidone-vinyl acetate copolymer that is soluble both in water and in alcohol. Insomnia is a common condition in the elderly and is associated with reduced quality of life and adverse outcomes. pharmachologic effect Combined preparation for the treatment of cough, has mucolytic and expectorant action, and also has anti-inflammatory activity. Register now and get a free online MSDS binder. TABLETS Mr. It is used to treat conditions in which pancreatic secretions are inadequate, such as surgical pancreatectomy, pancreatitis and cystic fibrosis. A high functionality and multifunctional excipient, it requires less complex processing, has high inherent functionality, and passes that functionality on to the drug formulation. Crospovidone is often combined with active ingredients in medications and dietary supplements to allow absorption of the active drug. 2, suggesting no significant difference in the elimination of docetaxel in the two populations. Показания по. 00001 Figure 3 Complexing ability of Soluplus® (MW 118,000) with an API. Pharmaceutical Granulation Processes, Mechanism, and the Use of Binders 2811001 1200 Granule size (GMD), um1002 100010031004 8001005 6001006 40010071008 2001009 01010 0 0. The approved therapeutic dose and shorter elimination half-life make Meclizine HCl a potential candidate to be formulated in extended release dosage form. An extensive body of EU-wide law covers the entire food production and processing chain within the EU, as well as imported and exported goods. 07 102 Kollidon VA 64 can be added to materials such as sorbitol, mannitol, starch, or direct compression aids, e. Affiliated tissues include eye , testes and lung , and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2). Polyvinylpyrrolidone is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Hence the objective of the present manuscript is to make a compilation review of research publications and patents on various applications of. Free access to more than 7+ million safety data sheets available online, brought to you by Verisk 3E. Search for a product. Three formulations of Kollidon® SR are in compliance with regu-latory requirements (Figure 6): • Kollidon® SR with high molecular weight HPMC (e. 75 Total tablet weight (mg) 994. K 90; K 90W; K 92; K 92 (vinyl polymer) Kollidon; Kollidon 12PF; Kollidon 17; Kollidon 17PF; Kollidon 25; Kollidon 30; Kollidon 90; Kollidon 90F; Kollidon CE 50/50; Kollidon K 15; Kollidon K 17; Kollidon K 25; Kollidon K 29/32; Kollidon K 30; Kollidon K 60; Kollidon K 90; Kollidon K 90F; Konkrepol AD 1; Konkrepol B; LFC; Lumiten PPR 8450. Pending recalls for the October 2nd, 2013 Enforcement Report PRODUCT Venlafaxine (Venlafaxine HCl) Extended Release, 225 mg, Rx only, a) 30 count (NDC 0131-3268-32) and b) 90 count (NDC 01310-3268. PVP polymer is readily soluble in cold water and the concentration is limited only by viscosity. Effect of kollidon 90F and poloxamer188 on etoricoxib to enhance it’s dissolution property by simple physical mixing and fusion techniques. Titik leleh: 1500 C Berat jenis : 1. The impact of the drug loading on the dissolution properties of these systems was also examined (5%, 15%, 30%, 50%, 70%, and 90% drug loading). What are DMSO and DMS? Dimethyl Sulfoxide (DMSO), one of the strongest organic solvents, has been used commercially for several decades. Every 30 min, the reaction mixture was stirred and subjected to a strong nitrogen sweep (for ~30 s). heated to above 90°C (194°F). 7% " Excellent china basf kollidon supplier polyvinylpyrrolidone price trade polyvinylpyrrolidone pvp k30. -[[4-(iodo-131I)phenyl]methyl]-. polivinilpirrolidona (Kollidon 30) y 3. Safety Data Sheet acc. Bulk Density. Kollidon VA 64 and Kollidon VA 64 Fine can be added to materials such as sorbitol, mannitol, starch, or direct compression aids, e. Kollidon VA64. Product Name: Kollidon 90 F Product Code: Language: English Regulation: GHS/CLP Manufacturer: BASF SE Carl- Bosch-Str. DT-loaded Kollidon® SR (KSR) and Eudragit® RS 100 (ERS) polymeric nanoparticles were prepared using Nano Spray-Dryer (B-90, Büchı Labortechnik AG, Flawil, Switzerland). Solid dispersion preparation. X 1 and X 2 are Kollidon CL-SF and Pearlitol 200 SD concentrations, respectively and as can be seen in Equation 5, have positive effects on dissolution rate. This research grade product is intended for use in R&D and development only. The dosage form can be prepared using simple, inexpensive tablet compression techniques. Understanding the biopharmaceutical implications of superdisintegrant variability (changes in material properties), variation (changes in excipient amount) and interchangeability (use of different excipient types with the same intended functionality) in oral drug. PVP K-30 polymer PVP K-30 polymer Description PVP (Polyvinylpyrrolidone) K-30 polymer is a hygroscopic, amorphous polymer. The independent variable factors selected were the weight by ratio of Aceclofenac to Kollidon 30 and the quantity of methanol in the formulation. BASF has been committed to the pharmaceutical industry since we introduced our original Kollidon ® in the early 20th century. Scientists are constantly trying to develop a better form of calcium. 15406/japlr. 0 Total qty of binary mixture 90. Le Kollidon® 90 F est un stabilisateur de suspension et un épaississant. Three formulations of Kollidon® SR are in compliance with regu-latory requirements (Figure 6): • Kollidon® SR with high molecular weight HPMC (e. microcrystalline cellulose 102. Kollidon 90 F is an exception in that, under these conditions, its stability can be guaranteed, as its K value gradually decreases. Piroxicam is a nonsteroidal oxicam derivative with anti-inflammatory, antipyretic and analgesic properties. 15 percent of PVP K 90 in aqueous solution boosts the viscosity of water from 1 mPa s to more than 5000 mPas and consequently, this type of PVP may be used as a thickener in various types of formulations (Table 1). Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. 3 Chemical and Physical Properties. Kollidon K-30. com 2015 - 016 Department of Pharmacy (Pharmaceutics) | Sagar savale 112-07-2016 Sagar Kishor Savale 2. Crospovidone is often combined with active ingredients in medications and dietary supplements to allow absorption of the active drug. Kollidon 90F, FlexiThix, and Carbomer 940 were directly dispersed into deionized water at room temperature with intensive agitation. *** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TR8370000 CHEMICAL NAME : Poly(1-vinyl-2-pyrrolidinone) homopolymer CAS REGISTRY NUMBER : 9003-39-8 LAST UPDATED : 199710 DATA ITEMS CITED : 21 MOLECULAR FORMULA : (C6-H9-N-O)x WISWESSER LINE NOTATION : /T5NVTJ AY*1*/ COMPOUND DESCRIPTOR : Tumorigen SYNONYMS/TRADE NAMES : * Agent AT 717 * Agrimer * Albigen A * Aldacol Q * AT 717 * Bolinan * 1. Kollidon® 30 is a polyvinylpyrrolidone polymer soluble in water and many organic solvents. Kollidon VA64 Soluplus Kollidon 12 PF Kollidon 17 PF Kollidon 30 Kollidon 90 F Kollidon SR Kollicoat MAE100P Kollicoat IR Kollicoat Protect Optimal melt viscosity range for HME Melt Viscosities Influence of Plasticizers on Extrusion Temperatures The addition of 10% plasticizer significantly decreases processing temperatures Pure Polymer + 10 %. 9% of the dose. Key Attributes. PHASE EQUILIBRIA AND DIFFUSION IN HPMCAS-ACETONE-WATER SYSTEM A Thesis in Chemical Engineering by Sheng-Wei Chiu 2015 Sheng-Wei Chiu Submitted in Partial Fulfillment of the Requirements for the Degree of Master of Science August 2015. Filaments for 3D printing were prepared by hot melt extrusion at 150°C with 10% and 20% w/w of haloperidol using Kollidon® VA64, Kollicoat® IR, Affinsiol™15 cP, and HPMCAS either individually. The example of a placebo tablet illustrated in Fig. The hardness, average weight, dimentions and adhesive force were evaluat-. Kollidon 25 is a rounded particle with the size of 50 – 90 µm with evenly spaced grooves on their surface. CAS Number(s):,9003-39-8 EINEC Number(s):. 2% w/w silica. Kollidon K25 Kollidon K-90 k25 MFCD00149016 POP Kollidon 25 k115 pvp2 pvp3 K-30 pvp4 PVPD. Kollidon must be stored tightly closed and protected from light at max. 2 Tablet binders Kollidon 25, 30 and 90 F Kollidon 25, 30 and 90 F give hard, free-flowing granules with a low pro-portion of fines and high binding strength when compressed into tablets. 30 m3/min Pump speed 3 mL/min Table 3. Conclusion Kollidon® 30 particles from 0. 9003-39-8) manufacturer Qingdao Kaimosi Biochemical Technology Co. 10, May 2003 Excipients & Actives for Pharma Imprint Trademarks are owned by BASF Aktiengesellschaft. Kollidon SR has a unique character of maintaining tablets geometric shape until the end of dissolution test, this is mainly due to the water insoluble content, polyvinyl acetate, forming 80% (w/w) of Kollidon SR, while the remaining content 20% (w/w) is the water soluble, polyvinylpyrrolidone, responsible for pore formation causing a diffusion. Background: This study involved a sensory evaluation of edoxaban orally disintegrating (OD) tablets in patients with nonvalvular atrial fibrillation who had been receiving the existing edoxaban film-coated tablets before the study. Ingredient(s): Lactose Monohydrate Dosage Form: Tablet Category: Granulation. Цифран ОД ⭐табл. The aim of current study was to explore the influence of three commonly used polymers, that is, cellulosics and noncellulosics, for example, Methocel K4M, Kollidon VA/64, and Soluplus, on the phase disproportionation and drug release profile of carbamazepine-succinic acid (CBZ-SUC) cocrystal at varying drug to polymer ratios (1 : 1 to 1 : 0. Kollidon ® 90 F is a soluble high-molecular povidone with highest binding properties within the povidone range. HPMC E4M (7: 326) Nama kimia : Cellulose hydroxypropyl methyl ether Sinonim : Hydroxypropyl methylcellulose (HPMC), hypromellosum Rumus bangun : R = H, atau CH3, or CH3CH(OH)CH2 Bobot molekul : 10. Le Kollidon® 25 et le Kollidon® 30 sont des liants pour comprimés pour la granulation humide. within 15-30 min (Kollidon® PF 12) or 30-60 min (Kollidon® VA 64), while FF release was complete within 20-30 min (Kollidon® VA 64) or 60 min (Soluplus®). Editor's note: Some chemicals in this database contain more information than others due to the original reason this information was collected and how the compilation was accomplished. Call a physician. Spherical paracetamol/ Kollidon® 30 particles were generated from 7 µm size (using the 7. Most sustained a mild TBI (90%) as a result of a fall (76%), 80% were admitted to the hospital ward/intensive care unit, and 69% had a positive head CT. Kollidon 90 F is the strongest wet-granulation binder on the market. hydroxypropyl methylcellulose (Methocelw K100M). Technical Information: Kollidon VA 64. Kollidon K-30. 'Kollidon 25' - chemical information, properties, structures, articles, patents and more chemical data. This technique requires a certain relative humidity, as the powder mixture must have a certain moisture content to bind properly. Effect of Ketoconazole: The effect of ketoconazole (a strong CYP3A4 inhibitor) on the pharmacokinetics of docetaxel was investigated in 7 cancer patients. Povidone K 12* Kollidon® 12PF BASF Povidone K 17* Kollidon® 17PF, Plasdone® C-15 BASF, ISP Povidone K 25 Kollidon® 25, Plasdone® K-25 BASF, ISP Povidone K 30 Kollidon® 30, Plasdone® K-29/32 BASF, ISP Povidone K 90 Kollidon® 90F, Plasdone® K-90 BASF, ISP Plasdone® K-90 D**, Plasdone® K-90 M** ISP. Structural Formula: [CH3(CH2)16COO]2Mg 3. Kollidon K-12. BuyersGuideChem. LYRICA CR extended-release tablets are administered orally and contain 82. It is mainly applied as a binder for granules and tablets, to improve the bioavailability of hardly soluble active compounds or in the field of controlled release. 7% " Excellent china basf kollidon supplier polyvinylpyrrolidone price trade polyvinylpyrrolidone pvp k30. Primarily used as a binder in granules and tablets, it can also be deployed to modify the viscosity of liquid dosage forms, and improve bioavailability of certain poorly soluble actives. Opadry yellow 19. Synonyms: Metallic stearate, Magnesium Salt. Aunque, Ludipress contiene disgregante, la desintegración de las tabletas tarda más que las tabletas que contienen α-lactosa monohidratada, Tabletosa y β-lactosa anhidra (27). com Kollidon ® 30 and Kollidon ® 25 require binder quantities of 2% and 5% related to the tablet weight. microcrystalline cellulose, whose own binding strength is inadequate, to give tablets with very good proper-ties. Source: BASF Corporation. A multilayer oral dosage form that provides controlled release of an active compound includes a non-erodible core containing a pharmaceutically active compound and/or a nutritionally active compound, and at least one release-modulating layer laminated to each side of the core layer. of page 1) 49. Kollidon® SR prepared with different amount of water as the granulation fluid 3. 0 Tolvaptan and Copovidone (Kollidon VA64) were taken in the above mentioned ratios ( Table 3) together through. For example, Kollidon ® 12 PF (K 12), Kollidon ® 30 (K 30), and Kollidon ® 90 F (K 90) possess average molecular weights of approximately 2500, 50000, and 1250000 g/mol, and T g s of 90°C, 149°C, and 156°C, respectively. Epub 2019 Feb 15. W ater and acetonitrile (90:10) 2S (USP39) [NOTE— System suitability solution: Transfer 10mg of 7 min. 15 percent of PVP K 90 in aqueous solution boosts the viscosity of water from 1 mPa s to more than 5000 mPas and consequently, this type of PVP may be used as a thickener in various types of formulations (Table 1). Description: Fine white, precipitated or milled, impalatable powder of low bulk density. ,Ltd Kollidon K 17;Kollidon K 25;Kollidon K 29/32;Kollidon K 30;Kollidon K 60;Kollidon K 90;Kollidon K 90F;Konkrepol AD 1;Konkrepol B;LFC;Lumiten PPR 8450;Lumiten PR 8450;Luvicross M;Luviskol K;Luviskol K 12;Luviskol K 120;Luviskol K 17;Luviskol K 17F;Luviskol. , 2007; Dixit RP et al. White Paper. Our Key Products for Pharmaceuticals application are:-Active Pharmaceutical Ingredients (API’s) for formulation and analysis; Wide variety of Polymers used for drug delivery system. Due to its bifunctional character, it is able to act as a matrix polymer for solid solutions on the one hand, and, on the other hand, it is capable of solubilizing poorly soluble drugs in aqueous media. Cremophor RH40, polyvinylpyrrolidone Kollidon 30 (PVP K30), polyvinylpyrrolidone Kollidon 90 (PVP K90), vinylprrolidone-vinylacetate copolymer Kollidon VA64 (PVP VA64), and Soluplus were kindly donated by BASF (Ludwigshafen, Germany). Raman mapping exposed very little intermigration of both drugs at the interface. Povidone K 12* Kollidon® 12PF BASF Povidone K 17* Kollidon® 17PF, Plasdone® C-15 BASF, ISP Povidone K 25 Kollidon® 25, Plasdone® K-25 BASF, ISP Povidone K 30 Kollidon® 30, Plasdone® K-29/32 BASF, ISP Povidone K 90 Kollidon® 90F, Plasdone® K-90 BASF, ISP Plasdone® K-90 D**, Plasdone® K-90 M** ISP. Kollidon® 90 F max. 0 per cent to 108. PVP K-60 and K-90 polymer are available commercially as 45 and 20 percent aqueous solutions, respectively. 0% Kollidon VA 64 2. Molecular weight of PEG unit is approximately 1000. Register now and get a free online MSDS binder. Affiliated tissues include eye , testes and lung , and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2). Kollidon 30 solid dispersion using methanol by solvent evaporation method (Prajapathi ST et al. A small tablet containing over 90% by weight of an orally active cephalosporin such as cephalexin and which utilizes as a binder polyvinyl pyrrolidone having a number average molecular weight of from 500,000 to 1,500,000. that exceeds ICH thresholds is to conduct a 90-day repeat-dose toxicology study for a chronic- use drug product. Kollidon® 90 F max. study of effects of post-compression curing on kollidon® sr based floating tablets: 90-93: sunil k jain, vilasrao j kadam, rajashree s hirlekar : case report : priapism induced with single oral dose of sildenafil: a rare case report: 94-95: deepak k jain : research articles. ru - это поиск по аптекам, просмотр и сравнение цен на лекарства в Кисловодске. Drug/Kollidon SR blends showed a superior compressibility, which was a Table 1: Point estimate and 90% confidence interval for max, AUC (CyDex Pharmaceuticals. Kollidon® VA 64 and Kollidon® VA 64 Fine are polyvinyl pyrrolidone-vinyl acetate copolymers. The 4-ASA loaded Kollidon VA64 filaments were extruded at 75 °C and printed at 90 °C. BASF supplies Kollidon® CL, Kollidon 020 40 60 80 100 12010 30 50 70 90 110 100 Kollidon® CL Kollidon. Kollidon® 90 F is a suspension stabilizer and thickener. Primarily used as a binder in granules and tablets, it can also be deployed to modify the viscosity of liquid dosage forms, and improve bioavailability of certain poorly soluble actives. PVP bersifat inert, larut air, dan alkohol. Selim Reza 1, Mohiuddin Abdul Quadir, Syed Shabbir Haider Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh Received 3 June 2003, Revised 15 June 2003, Accepted 5 August 2003. The impact of the drug loading on the dissolution properties of these systems was also examined (5%, 15%, 30%, 50%, 70%, and 90% drug loading). Expand this section. Ďalšie zložky sú: povidón 25 (Kollidon 25), kyselina vínna, citronan sodný, kyselina citrónová, kyselina askorbová obalená etylcelulózou, acesulfam, draselná soľ; pomarančová aróma v prášku 57160, zázvorová aróma, farbivo MicroCap P-21-WSS-P-125, sacharóza. Kollidon 90 F: 81. com Kollidon ® 30 and Kollidon ® 25 require binder quantities of 2% and 5% related to the tablet weight. 880) and a lso between hardnes s of tab lets and re lease r ate constant (R 2 =0. Product search for: Povidone Ph. Poly[1-(2-oxo-1-pyrrolidinyl)-1,2-ethanediyl],. KOLLIDON® 25 | KOLLIDON® 30; KOLLIDON® 90 F ; KOLLIDON® VA 64; Liberación controlada. Conclusion In summary, this article highlights the importance of commonly used surfactant/lipid based self-emulsifying delivery systems. Telefax: (595 21) 673 250 (R. 3) 용도 직타형 부형제. Synonyms: Metallic stearate, Magnesium Salt. 5 Figure 6 Swelling of Polyplasdone crospovidones is independent of pH Compaction force (kN) Breaking forc e (k p) 50 40 30 20 10 0 1 J. koletr koletra kardil kesperidone ketian kodaflextxib kbe902 kh590 kbm-802 kumarin kirel kavatin kavahin kawain,dl kawain kavain,dl kefral kudesan kathoncg kollidon k25 kollidon k-90 kollidon 25 k25 k115 k-30 k60 kolima35 kolima10 kitonbluea karstenite. Call a physician. The solutions were spray dried on a Bend miniSD spray drying unit and the resulting samples were dried at 25 °C under reduced pressure. 9 μm, equivalente a 23% en relación al valor medio. Ashland offers a comprehensive range of Plasdone povidones (PVP). 45, 208‡ T deg. 10 Hygroscopicity Kollidon VA 64 and Kollidon VA 64 Fine absorb only about one third of the quantity of water absorbed by povidone, e. k 90; kollidon; kollidon 12pf; kollidon 17; kollidon 17pf; kollidon 25; kollidon 30; kollidon 90; kollidon 90f; kollidon ce 50/50; kollidon k 25; kollidon k 30; kollidon k 90; lfc; lumiten pr 8450; luviskol k 12; luviskol k 17; luviskol k 25; luviskol k 30; luviskol k 60; luviskol k 80; luviskol k 90; luviskol kpo; mpk 90; n-vinyl-2-pyrrolidone. Kollidon 25 is a rounded particle with the size of 50 - 90 µm with evenly spaced grooves on their surface. Medium molecular weight binder with low peroxide level thanks to Peroxeal packaging leading to extended shelf life. Comfort and Compatibility of Silicone Hydrogel Contact Lenses Ngai Keung Tam Brigham Young University - Provo Follow this and additional works at:https://scholarsarchive. The tablets were developed with lactose, Kollidon® 90 F (povidone USP) and Poliox® WSR 301 NF (polietileneglicol NF) in different concentration ratios, based on the statistical ¨simplex¨ mixture aproach. 25 Parameters F-1 F-2 F-3 F-4 F-5 LBD (g/ml) 0. Kollidon CL-M. The approved therapeutic dose and shorter elimination half-life make Meclizine HCl a potential candidate to be formulated in extended release dosage form. 00001 Figure 3 Complexing ability of Soluplus® (MW 118,000) with an API. PVP polymer is readily soluble in cold water and the concentration is limited only by viscosity. Kollidon VA 64 is a vinylpyrrolidone-vinyl acetate copolymer that is soluble both in water and in alcohol. Povidone(Cas No. 9% of the dose. The difference (f1) and similarity (f2) factors was found to be 89. s at temperatures as high as 180°C. Tutte le informazioni che cerchi in un unico sito di fiducia. sized, controlled release drug delivery system was aimed in this study. Ludipress® LCE A new direct compression excipient. The retention time of 2-pyrrolidinone is about 2S (USP39)] vinylpyrrolidinone and 500mg of vinyl acetate to a Injection volume: 50µL 100-mL volumetric flask, and dissolve in and dilute System suitability with methanol to volume. 产品特性:各种可溶性Kllidon产品都是以流动性极佳的米白色粉状品供货。它们带有轻微的特殊气味,而且基本上是无味道的。 包装规格:25kg. Kollidon® 90 F is a high molecular weight binder and suspension stabilizer. Kollidon® 90 F is a soluble high-molecular povidone with highest binding properties within the povidone range. Table 2 shows the amount of ingredients used for the. Hinweise. 0% Orange flavour. Animal Cognition Brochure. Your new online MSDS binder is a place for you to store the material safety data sheets you need to deploy. Sagar Kishor Savale [Department of Pharmaceutics] [email protected] 30, 90, VA64), kollidon insoluble (CL-M, CL-F, CL-SF), and kollidon SR. BASF has been committed to the pharmaceutical industry since we introduced our original Kollidon ® in the early 20th century. FDA Drug Establishment Registration. 2015;1(1):1‒3. A multilayer oral dosage form that provides controlled release of an active compound includes a non-erodible core containing a pharmaceutically active compound and/or a nutritionally active compound, and at least one release-modulating layer laminated to each side of the core layer. Povidone formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents. formulations released 90% of drug within 120 minutes except F4 formulation. The product shows a decrease in release rate in both 20 and 40% ethanol media (Fig. This technique requires a certain relative humidity, as. The above description is considered that of the preferred embodiment only. 30 m3/min Pump speed 3 mL/min Table 3. Povidone k30 has the molecular formula of (C6H9NO)n and appears as a white to slightly off-white powder. KOLLIDON CL-F offer offer. 3 Hygroscopicity of Kollidon VA 64 and Kollidon 30 EMP 050602e-05 June 2008 Page 6 of 16 Kollidon VA 64 and VA 64 Fine. BASF(ビーエーエスエフ)は持続可能な将来のために、化学でいい関係をつくります。また、経済的な成功、環境保護、そして社会的責任を同時に実現しています。 BASFは科学とイノベーションを通して現代社会や将来の. 马可波罗网 > 原料辅料、初加工材料 > 催化剂、助剂、填充剂 > 涂料助剂 > 成膜助剂 > 聚维酮K90 kollidon 90 聚维酮K90 kollidon 90 查看详情>> 试试键盘 ← → 键. This technique requires a certain relative humidity, as. At Essential Drugs we provide the pharmaceutical industry with active ingredients (APIs) and excipients adapted to all the sector's needs. Povidone k30 has the molecular formula of (C6H9NO)n and appears as a white to slightly off-white powder. 07 102 Kollidon VA 64 can be added to materials such as sorbitol, mannitol, starch, or direct compression aids, e. [0018] It is possible if desired to employ in addition to PVP other binders such as polyvinyl acetate (e. MATERIALS 2. 30 m3/min Pump speed 3 mL/min Table 3. 5% 5kN/cm GL200 2% 5kN/cmGL200 0 % 12kN/cm GL200/PVP25 Fig. The hardness, average weight, dimentions and adhesive force were evaluat-. Taurolidine for injection was diluted from the 2% stock solution by the addition of 5% Kollidon 17PF. Pancreatin is composed of amylase, lipase and protease. Kollidon SR is a co-spray-dried powder composed of 80% PVAc, 19% PVP, 0. Цены на Гропивирин, наличие в интернет-аптеках Теплодар. Si se toma el valor de X 90 ≤ 4. A – (1636) Olivos Buenos Aires - Tel: (54 11) 4711 1769 [email protected] 9 mg were printed at 90°C. 5, the complex viscosity of the Affinisol™ HPMC HME polymers at 0. Nano Spray Dryer B-90 to generate new formulations for drug delivery and pharmaceutical applications. An ideal mixing ratio of 1:2 w/w between paracetamol and Kollidon® 30 was found to. It consists of lactose powder coated with polyvinyl pyrrolidone and crospovidone (23). Substituting Kollidon 25 or Kollidon 30 by Kollidon 90 F would be particularly interesting for obtaining greater hardness without increasing the pressure. Effect of kollidon 90F and poloxamer188 on etoricoxib to enhance it's dissolution property by simple physical mixing and fusion techniques. An online version of the USDOT's listing of hazardous materials from 49CFR 172. Patient average age was 78y (range: 65‐98y). Telefax: (595 21) 673 250 (R. Thành phần: Hoạt chất: Glimepirid 2 mg Metformin hydrochlorid 500 mg Tá dược: Lactose monohydrat, Avicel M101, Natri starch glycolat, Crospovidon, Kollidon K30, Magnesi stearat, HPMC 615, HPMC 606, Talc, Titan dioxyd, PEG 6000. At Essential Drugs we provide the pharmaceutical industry with active ingredients (APIs) and excipients adapted to all the sector's needs. Inhalation: If inhaled, remove to fresh air. Table 3, for example, is suitable for direct compression. We also manipulated the drug release from the kollidon SR KT 90% with a very low first-pass metabolism, its short biological half-life (4-6hr) produces many adverse effects, such as upper. SAFETY DATA SHEET AEROSIL® 200 Material no. the mechanical properties of Paracetamol containing tablets. Kollidon 90 F from BASF North America. 4% Macrogol 6000, powder 2. Application PVP has a wide range of usage such as: • an adhesive for making gluesticks and metal adhesives. "Kollidon, Polyvinylpyrrolidone for the pharmaceutical industry" (BASF, B 390 e, 3rd edition 1996). polivinilpirrolidona (Kollidon 30) y 3. k 90; kollidon; kollidon 12pf; kollidon 17; kollidon 17pf; kollidon 25; kollidon 30; kollidon 90; kollidon 90f; kollidon ce 50/50; kollidon k 25; kollidon k 30; kollidon k 90; lfc; lumiten pr 8450; luviskol k 12; luviskol k 17; luviskol k 25; luviskol k 30; luviskol k 60; luviskol k 80; luviskol k 90; luviskol kpo; mpk 90; n-vinyl-2-pyrrolidone. 90 values but Kollidon® CL-SF at a concentration of 4% was found to show the best results (T 50 = 10. 2% polyvinyl pyrrolidone (Kollidon 30) and 3. AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. of page 2) 49. Kollidon SR has a unique character of maintaining tablets geometric shape until the end of dissolution test, this is mainly due to the water insoluble content, polyvinyl acetate, forming 80% (w/w) of Kollidon SR, while the remaining content 20% (w/w) is the water soluble, polyvinylpyrrolidone, responsible for pore formation causing a diffusion. Last updated on Nov 28, 2018. crospovidone (Polyplasdone XL, Kollidon CL) Mechanism of Action: Water wicking, swelling and possibly some deformation recovery. View Md Tahsin’s profile on LinkedIn, the world's largest professional community. A wide variety of kollidon k30 options are available to you, solution supplier china basf kollidon supplier pvp 90 water plasdone k29 k32 medicine tablet binding tablet binder pvp k30 manufacturer 30 n kollidon povidone va 64 kollidon k25 povidone k30 tablet film coating povidone k30 pharmaceutical cosmetical binder kollidon k30 kollidon. MAGNESIUM STEARATE [86-90] 1. The K-value of povidone having a statedK-value of 15 or less is 85. Raman mapping exposed very little intermigration of both drugs at the interface. Final blend of milled granules were prepared by adding additional 2%. J Anal Pharm Res. Nano Spray Dryer B-90 to generate new formulations for drug delivery and pharmaceutical applications. 14 Polyvinylpyrrolidone Povidon K 90 Kollidon 90F · Identification number(s) - · EC number: 618-363-4 * 4 First-aid measures · 4. Search for a product. Description The foundations of modern acetylene chemistry were laid by Reppe at BASF. KOLLIDON CL offer offer. Povidone EP (Kollidon 90) Stearic acid BP Acrylic polymer coating (Eudragit E) Talc BP Titanium dioxide BP Polyethylene glycol 300 BP 6. 8% SLS and 0. Damit lässt sich aus dem K-Wert indirekt auf den Grad der Polymerisation und damit die Kettenlänge schließen. Soluplus is a polymeric solubilizer with an amphiphilic chemical structure, which was particularly developed for solid solutions. Tablet properties Weight 516 mg Diameter 12 mm Form biplanar Hardness 90 N Disintegration <1 min Friability 0. The powder is unctuous and readily adheres to skin. k 90; kollidon; kollidon 12pf; kollidon 17; kollidon 17pf; kollidon 25; kollidon 30; kollidon 90; kollidon 90f; kollidon ce 50/50; kollidon k 25; kollidon k 30; kollidon k 90; lfc; lumiten pr 8450; luviskol k 12; luviskol k 17; luviskol k 25; luviskol k 30; luviskol k 60; luviskol k 80; luviskol k 90; luviskol kpo; mpk 90; n-vinyl-2-pyrrolidone. Resource Center How To Guide. 马可波罗网 > 原料辅料、初加工材料 > 催化剂、助剂、填充剂 > 涂料助剂 > 成膜助剂 > 聚维酮K90 kollidon 90 聚维酮K90 kollidon 90 查看详情>> 试试键盘 ← → 键. 02 10 04 30 06 50 08 70 0 90 100 Normalized swell volume pH 7. 0 Total qty of binary mixture 90. within 15-30 min (Kollidon® PF 12) or 30-60 min (Kollidon® VA 64), while FF release was complete within 20-30 min (Kollidon® VA 64) or 60 min (Soluplus®). POLIVINILPIROLIDONA Av. Titik leleh: 1500 C Berat jenis : 1. Ensure that medical personnel are aware of the material(s) involved, and. In comparison to Kollidon SR, microcrystalline cellulose (MCC) was used. sildenafil citrate. Le Kollidon® VA 64 et le Kollidon® VA 64 Fine sont utilisés en tant que liants dans la granulation humide et en tant qu'agent d'enrobage. Modifications of the invention will occur to those skilled in the art and to those who make or use the invention. The tablets were developed with lactose, Kollidon® 90 F (povidone USP) and Poliox® WSR 301 NF (polietileneglicol NF) in different concentration ratios, based on the statisticaïsimplexixture. DMSO also dissolves many inorganic salts, particularly transition metals nitrates, cyanides and dichromates. 0 µm spray cap). The dosage form can be prepared using simple, inexpensive tablet compression techniques. All of three formulations have. Date HS Code Description Origin Country Port of Discharge Unit Quantity Value (INR) Per Unit (INR) Nov 22 2016: 39059990: KOLLIDON 30 (POLYVINYLPYRROLIDONE) (PVPK) (GERMANY). Soluplus is a polymeric solubilizer with an amphiphilic chemical structure, which was particularly developed for solid solutions. 00001 Figure 3 Complexing ability of Soluplus® (MW 118,000) with an API. Effect of Angular Frequency on Torque: Affinisol™ HPMC HME Polymers vs. If Kollidon 90 F is kept refrigerated, its K value decreases more slowly. Kollidon SR (polyvinyl acetate/polyvinylpyrrolidone, 80/20 w/w) matrix tablets with various porosities (10–30% v/v) containing model drugs with different solubilities (C s = 10–170 mg/ml) and in different amounts (A = 10–90% w/w) were prepared by direct compression and characterized by drug release and mass loss studies. Table 2 shows the amount of ingredients used for the. It consists of lactose powder coated with polyvinyl pyrrolidone and crospovidone (23). Купить Basf Kollidon Cl М оптом из Китая. Polyvinylpyrrolidone is a white powder. 9 ) (Traynor et al. , 3-5-1, Nihonbashi Honcho, Chuo-ku, Tokyo 103-8426 Japan. Kollidon VA 64 possesses a high plasticity of over 90 % that remains constant from 10 to 18 to 25 kN. Piroxicam is a commonly used nonsteroidal antiinflammatory drug (NSAID) that is available by prescription only and is used in therapy of chronic arthritis. 90 µm -130 µm: Chemical name: Polyvinylpyrrolidone, crosslinked: CAS-No: 9003-39-08: Regulatory Status: Crospovidone in Ph. 1 Information on toxicological effects. 3% of polymer, respectively. Registrar Corp helps companies comply with U. General advice If you feel unwell, seek medical advice (show the label where possible). Polomska, 1 Steven T. Animal Cognition Brochure. , 2007; Dixit RP et al. It is used to treat conditions in which pancreatic secretions are inadequate, such as surgical pancreatectomy, pancreatitis and cystic fibrosis. An online version of the USDOT's listing of hazardous materials from 49CFR 172. Kollidon K-17. 7 Bulk density The bulk density of Kollidon® is determined according to Ph. 4 Spectral Information. Le Kollidon® VA 64 et le Kollidon® VA 64 Fine sont utilisés en tant que liants dans la granulation humide et en tant qu'agent d'enrobage. Hinweise. Article (PDF Available) were obtained by hot melt extrusion at 70°C and ramipril printlets with a dose equivalent of 8. Kollidon SR is a blend of polyvinyl acetate and povidone (K 30) in the ratio 8:2 for use as matrix-forming agent. Free access to more than 7+ million safety data sheets available online, brought to you by Verisk 3E. Typical collection times were 5-30 min, using 3-5 mW of 244 nm excitation energy. Primarily used as a binder in granules and tablets, it can also be deployed to modify the viscosity of liquid dosage forms, and improve bioavailability of certain poorly soluble actives. POVIDONE KOLLIDON 90F: Brand Name English view: view: KOLLIDON 90F: Brand Name English view: view: POLYVINYLPYROLIDONE K-90: Common Name English view: view: POVIDONE K90F [II] Common Name English view: view: POVIDONE K90 [II] Common Name English view: view: POVIDONE K90F Common Name English view. Binding Kollidon ® 25/Kollidon 30 P The original. Kollidon 90 F BASF North America: Binder: Tablet binding, Thickener, Stabilizers of suspensions, Reduces sedimentation, crystallization inhibition: Get quote White Paper SDI Phase. Moreover, at pH 6. 0% Kollidon VA 64 2. 9003-39-8 - Povidone [USAN:USP:INN:BAN] - Similar structures search, synonyms, formulas, resource links, and other chemical information. 02 (theoretical loading - 3 wt%) and the amount of drug in the final printlets was 9. Three formulations of Kollidon® SR are in compliance with regu-latory requirements (Figure 6): • Kollidon® SR with high molecular weight HPMC (e. Ces cookies permettent d’interagir depuis le site Le Vidal avec les modules sociaux et de partager les contenus du site du avec d’autres personnes, lorsque vous cliquez sur le module "Partager", de Facebook et de Twitter, par exemple. ar FICHA DE DATOS DE SEGURIDAD. Kollidon VA64 (KV64) (M W = 45 000−47 000 g/mol) with degradation temperature equal to 543 K 26 and Soluplus (SOP) (M W = 90 000−140 000 g/mol) with degradation temperature equal to 551 K 26. The coating solution was applied as described in example 4 to the base-coated tablets described above. Selim Reza 1 , Mohiuddin Abdul Quadir, Syed Shabbir Haider Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka , Dhaka-1000, Bangladesh. For example, Kollidon ® 12 PF (K 12), Kollidon ® 30 (K 30), and Kollidon ® 90 F (K 90) possess average molecular weights of approximately 2500, 50000, and 1250000 g/mol, and T g s of 90°C, 149°C, and 156°C, respectively. The k number refers to the mean molecular weight of the povidone. -[[4-(iodo-131I)phenyl]methyl]-. Povidone(Cas No. An online version of the USDOT's listing of hazardous materials from 49CFR 172. PROSOLV ® SMCC, silicified microcrystalline cellulose, is a unique combination of microcrystalline cellulose (MCC) and colloidal silicon dioxide (CSD). Si se toma el valor de X 90 ≤ 4. INTRODUCTION. Synonyms: Metallic stearate, Magnesium Salt. Цифран ОД ⭐табл. KOLLIDON® 25 | KOLLIDON® 30; KOLLIDON® 90 F ; KOLLIDON® VA 64; Liberación controlada. Since then we have continuously expanded our solution offer. Pancreatin is composed of amylase, lipase and protease. It is considered to be physiologically inert. All ODTs released over 90% drug at the end of 10 min (Figure 2). Date : 13/05/2019. Most sustained a mild TBI (90%) as a result of a fall (76%), 80% were admitted to the hospital ward/intensive care unit, and 69% had a positive head CT. The dosage form can be prepared using simple, inexpensive tablet compression techniques. Odor and taste are slight but characteristic. BASF Good flow, creamier Kollidon CL-SF. Kollidon CL. study of effects of post-compression curing on kollidon® sr based floating tablets: 90-93: sunil k jain, vilasrao j kadam, rajashree s hirlekar : case report : priapism induced with single oral dose of sildenafil: a rare case report: 94-95: deepak k jain : research articles. 14 Polyvinylpyrrolidone Povidon K 90 Kollidon 90F · Identification number(s) - · EC number: 618-363-4 * 4 First-aid measures · 4. Table 3, for example, is suitable for direct compression. The tablets were developed with lactose, Kollidon® 90 F (povidone USP) and Poliox® WSR 301 NF (polietileneglicol NF) in different concentration ratios, based on the statistical "simplex" mixture. 0 µm spray cap) down to 600 nm (4. It acts as iodophor in iodine-polyvinylpyrrolidone. The k number refers to the mean molecular weight of the povidone. Kollidon VA64 0 100 200 300 400 500 600 0 50 100 150 200 Median Particle Diameter (Pm) Screw Speed (rpm) Soluplus Eudragit EPO Kollidon VA64 Continuous Mode Recirculation Mode 0. , 2007; Dixit RP et al. The dosage form can be prepared using simple, inexpensive tablet compression techniques. Comparative evaluation of plastic, hydrophobic and hydrophilic polymers as matrices for controlled-release drug delivery. Document Type : Brochures. Kollidon® SR is a polyvinyl acetate polyvinyl pyrrolidone copolymer. After sieving, this material was dried and then resieved. Sites and Contacts. *Please select more than one item to compare. Medium molecular weight binder with low peroxide level thanks to Peroxeal packaging leading to extended shelf life. Drug/Kollidon SR blends showed a superior compressibility, which was a Point estimate and 90% confidence interval for max, AUC 0-t and AUC 0-Formulation Comparison C max AUC 0-t AUC 0-Solution vs (CyDex Pharmaceuticals Inc. It is considered to be physiologically inert. Almost 90% of formulations available in the market are solid oral forms, with tablet forming the main bulk of it. The hardness, average weight, dimentions and adhesive force were evaluat-. Dirección: Avellaneda, Buenos AIres, Argentina Oportunidad # 1854379 Fecha: más de 12 meses Mensaje al comprador Ver detalle. 143RP 1-Vinyl-2-pyrrolidinone polymer 1-Vinyl-2-pyrrolidone homopolymer 1-Vinyl-2-pyrrolidone polymer 2-Pyrrolidinone,1-vinyl-, polymers (8CI) 40K 40K (vinyl polymer) ACP 10 Agent AT 717 Agrimer 15 Agrimer 30 Agrimer 90 Agrimer K 30 Albigen A Aldacol Q Antaron P 804 Antitox Vana AT 717 B7509 Bolinan Cevian A 88036 Deltaspeed AF Discol K 30L. Formulation of Release Controlling Layers as Upper and Bottom Layers for Nifedipine Sustained Release Tablets (mg) 1 234 567 Kollidon VA64 100 HPMC K100M 100 HPMC K15M 100 PEO 8000K 100 PEO 4000K 100 Carbopol 100 L-HPC 100 Lactose 62 Croscamellose. The solutions were spray dried on a Bend miniSD spray drying unit and the resulting samples were dried at 25 °C under reduced pressure. Proulx, 1 Davide Brambilla, 2 Daniel Fehr, 3 Mathias Bonmarin, 3 Simon Brändli, 4 Mirko Meboldt, 4 Christian Steuer, 1 Tsvetina Vasileva, 1 Nils Reinke, 3 Jean-Christophe Leroux, 1 and Michael Detmar 1. The swelling behavior of Ac-Di-Solw depended on the ionic strength and the pH of the medium due to a competition for free water and the acidic nature of this polymer. The polymer can be effectively used to bind and remove stains through hydrogen bonding with chemical. Kollidon K-17. Table 3, for example, is suitable for direct compression. 2 Names and Identifiers. Kollidon® 30 LP is therefore particularly suited for the use as binder for peroxide sensitive drugs in solid oral dosage forms. 110780-Povidone K30, Ph. Kollidon K-30. Kollidon 90 F is an exception in that, under these conditions, its stability can be guaranteed, as its K value gradually decreases. They are linear nonionic polymers that are soluble in water and organic solvents and are pH stable. 型号:kollidon 90 F. All of three formulations have. 90 - 94% (1) Other (1) pH Value. , European and Japanese pharmacopoeia specifications for Povidone. Kollidon® VA 64; Kollidon® VA 64 Fine; Lutrol® micro 68; Soluphor® P; Solutol® HS 15; Descargar catálogo [Ph] Nombre y. Povidone-Iodine Solution Lernapharm (Loris) Inc. Among the six formulations, release was prompt in F1 formulation because of usage of higher concentration of polymer Kollidon SR. Active ingredients were incorporated into the gel uniformly. Kollidon VA64 Soluplus Kollidon 12 PF Kollidon 17 PF Kollidon 30 Kollidon 90 F Kollidon SR Kollicoat MAE100P Kollicoat IR Kollicoat Protect Optimal melt viscosity range for HME Melt Viscosities Influence of Plasticizers on Extrusion Temperatures The addition of 10% plasticizer significantly decreases processing temperatures Pure Polymer + 10 %. Kollidon 90 F: 81. 4% Cyclamate sodium 2. Although the standard is calcium carbonate, other mild acids are often paired with this bone-building mineral. Toggle navigation. phosphate, 3) Kollidon® VA-64 Fine Lubricant (Magnesium stearate) !Roller compaction processing parameters (varied): !! Ribbon thickness, roller force, roller speed !Roller compaction parameters (not varied): !!Mill speed (90 rpm) and granulator screen (0. See the complete profile on LinkedIn and discover Md’s connections and. Application PVP has a wide range of usage such as: • an adhesive for making gluesticks and metal adhesives. HSN Code: 39059990. Conclusion In summary, this article highlights the importance of commonly used surfactant/lipid based self-emulsifying delivery systems. 2 shows that tablets of twice the hard- 1,0 0,9 0,8 0,7 0,6 0,4 0,5 Kollidon VA 64 Kollidon 30 Mc. Date HS Code Description Origin Country Port of Discharge Unit Quantity Value (INR) Per Unit (INR) Sep 12 2016: 39059990: KOLLIDON(R) 90 F (POVIDONE K-90 IP) Germany.